# Wright GFR Equation Calculator

Estimates glomerular filtration rate (GFR) based on serum creatinine, patient age, gender and body surface.

Refer to the text below the tool for more information about the Wright formula and its usage.

The Wright equation may be used to estimate the glomerular filtration rate, as measure of renal function, especially accurate in the case of elderly patients, based on the patient’s age, gender, measured serum creatinine and body surface area (by DuBois’ formula – from height and weight).

`GFR (ml/min) = ((6580 – (38.8 × Age)) × BSA × (1 – (0.168 × Sex)))/SCr`

Where:

• Gender value is 0 for men and 1 for women;
• `BSA DuBois’s formula = 0.007184 x (Height in cm)725 x (Weight in kg)0.425`
• Serum creatinine is expressed in µmol/L. In case the serum creatinine is given in mg/dL, the conversion from mg/dL to µmol/L is: 1 mg/dL = 88.4 µmol/L.

Patient Age
Patient Gender
Serum Creatinine (SCr)
Body Surface Area (BSA) by DuBois?
BSA (DuBois)
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Steps on how to print your input & results:

1. Fill in the calculator/tool with your values and/or your answer choices and press Calculate.

2. Then you can click on the Print button to open a PDF in a separate window with the inputs and results. You can further save the PDF or print it.

Please note that once you have closed the PDF you need to click on the Calculate button before you try opening it again, otherwise the input and/or results may not appear in the pdf.

## About the Wright Equation

GFR is the gold standard for the evaluation of kidney function but its actual measurement is difficult to perform in routine practice therefore, an estimation based on formulas that employ patient’s clinical data is often used.

The Wright equation provides one of those ways that estimate the glomerular filtration rate, as measure of renal function, based on the patient’s age, gender, measured serum creatinine and body surface area (by DuBois’ formula – from height and weight).

Developed in 2001, the Wright formula is particularly recognized as the most accurate and least biased formula for the estimation of GFR in elderly patients with a GFR >50 ml/min.

`GFR (ml/min) = ((6580 – (38.8 × Age)) × BSA × (1 – (0.168 × Sex)))/SCr`

Where:

• Gender value is 0 for men and 1 for women;
• `BSA DuBois’s formula = 0.007184 x (Height in cm)725 x (Weight in kg)0.425`
• Serum creatinine is expressed in µmol/L. In case the serum creatinine is given in mg/dL, the conversion from mg/dL to µmol/L is: 1 mg/dL = 88.4 µmol/L.

The Wright equation, similar to the Jelliffe one, does not require a patient's height or weight because it describes unstable renal function normalized to a body surface area of 1.73 m2.

In the general population, it was observed that GFR declines steadily with aging, approximately 38% of elderly adults (70+) have an estimated glomerular filtration rate (eGFR) < 60 ml/min, with most having moderate reductions in eGFR in the 30-59 ml/min range.

Lower eGFR levels are associated with risk for adverse events such as cardiovascular disease (CVD), mortality, and end-stage renal disease (ESRD).

Other ways of estimating creatinine clearance or glomerular filtration rate to evaluate renal function include:

## References

### Original reference

Wright JG, Boddy AV, Highley M, Fenwick J, McGill A, Calvert AH. Estimation of glomerular filtration rate in cancer patients. Br J Cancer. 2001; 84(4):452-9.

### Other references

Marx GM, Blake GM, Galani E, Steer CB, Harper SE, Adamson KL, Bailey DL, Harper PG. Evaluation of the Cockroft-Gault, Jelliffe and Wright formulae in estimating renal function in elderly cancer patients. Ann Oncol. 2004; 15(2):291-5.

DuBois D, DuBois DF. A formula to estimate the approximate surface area if height and weight be known. Arch Int Med 1916; 17:863-71.

Specialty: Nephrology

System: Renal

Year Of Study: 2001

Article By: Denise Nedea

Published On: October 25, 2020 · 12:00 AM

Last Checked: October 25, 2020

Next Review: October 25, 2025