Pulmonary Function Tests (PFTs)

Determines the most commonly tested respiratory parameters and capacities based on easily obtained data and volumes.

Refer to the text below the calculator to learn more about pulmonary function tests (PFTs), their methods, results and interpretations.

Pulmonary function tests (PFTs) are non-invasive tests that evaluate the respiratory function, essentially how well the lungs are working.

During PFTs , there are several parameters and volumes measured, some of which can also be estimated from patient data such as age, gender, height or ethnicity, which is what this calculator sets out to do, so you can have an idea of possible values, before or after your actual spirometry or plethysmography tests.

Reference ranges for the pulmonary parameters and capacities commonly determined in pulmonary function tests along with their formulas:

 Parameter Formula Normal range Tidal Volume (TV) IBW male = 50kg + 2.3 x (Height in inches – 60)IBW female = 45.5kg + 2.3 x (Height in inches – 60) 500 – 780 mL Minute Volume (VE) VE in mL/min = Tidal volume (Vt) in mL x Respiratory rate (RR) in resp/min 70 – 110 mL/kg/min Peak Expiratory Flow Rate (PEFR) Children PEFR = ((Height in cm - 100) x 5) + 100Adult Men = (((Height in m x 5.48) + 1.58) - (Age x 0.041)) x 60Adult Women = (((Height in m x 3.72) + 2.24) - (Age x 0.03)) x 60 390 – 740 L/min Forced Vital Capacity (FVC) FVC = Race x 1.15 x [(0.0443 x Height) - (0.026 x Age) - 2.89] 3.0 – 5.0 L Forced Expiratory Volume (FEV1) FEV1 = Race x 1.08 x [(0.0395 x Height) - (0.025 x Age) - 2.6] 2.4 – 4.0 L Vital Capacity (VC) VC for men = [(27.63 – 0.112 x Age in years) x Height in cm] / 1000VC for women = [(21.78 – 0.101 x Age in years) x Height in cm] / 1000 3.0 – 5.0 L Functional Residual Capacity (FRC) FRC = Expiratory Reserve Volume (ERV) + Residual Volume (RV) 2.0 – 4.0 L Total Lung Capacity (TLC) TLC = Inspiratory Reserve Volume (IRV) + Tidal Volume (TV) + Expiratory Reserve Volume (ERV) + Residual Volume (RV) 4.0 – 6.0 L

Age
Gender
Race
Height
Respiratory rate

BData Optional (If Known) for Pulmonary Capacities

Inspiratory reserve volume (IRV)
Expiratory reserve volume (ERV)
Residual volume (RV)
Tidal volume (TV)
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Pulmonary function tests (PFTs) are non-invasive tests that evaluate the respiratory function, essentially how well the lungs are working.

 Parameter Formula Normal range Tidal Volume (TV) IBW male = 50kg + 2.3 x (Height in inches – 60)IBW female = 45.5kg + 2.3 x (Height in inches – 60) 500 – 780 mL Minute Volume (VE) VE in mL/min = Tidal volume (Vt) in mL x Respiratory rate (RR) in resp/min 70 – 110 mL/kg/min Peak Expiratory Flow Rate (PEFR) Children PEFR = ((Height in cm - 100) x 5) + 100Adult Men = (((Height in m x 5.48) + 1.58) - (Age x 0.041)) x 60Adult Women = (((Height in m x 3.72) + 2.24) - (Age x 0.03)) x 60 390 – 740 L/min Forced Vital Capacity (FVC) FVC = Race x 1.15 x [(0.0443 x Height) - (0.026 x Age) - 2.89] 3.0 – 5.0 L Forced Expiratory Volume (FEV1) FEV1 = Race x 1.08 x [(0.0395 x Height) - (0.025 x Age) - 2.6] 2.4 – 4.0 L Vital Capacity (VC) VC for men = [(27.63 – 0.112 x Age in years) x Height in cm] / 1000VC for women = [(21.78 – 0.101 x Age in years) x Height in cm] / 1000 3.0 – 5.0 L Functional Residual Capacity (FRC) FRC = Expiratory Reserve Volume (ERV) + Residual Volume (RV) 2.0 – 4.0 L Total Lung Capacity (TLC) TLC = Inspiratory Reserve Volume (IRV) + Tidal Volume (TV) + Expiratory Reserve Volume (ERV) + Residual Volume (RV) 4.0 – 6.0 L

During PFTs, there are several parameters and volumes measured, some of which can also be estimated from patient data such as age, gender, height or ethnicity, which is what this calculator sets out to do, allowing to determine the possible values, before or after actual spirometry or plethysmography tests.

Spirometry tests are performed with the use of a spirometer, which is a device with a mouthpiece hooked up to a small electronic machine. Plethysmography tests are performed with a plethysmograph, which is a box similar to a short telephone booth, in which the patient is placed when performing the inhalation and exhalation tests.

Both methods are non-invasive, safe and easy to use but some of the risks of the procedure you may wish to know about include dizziness during the tests, shortness of breath during tests, coughing, asthma attack brought on by deep inhalation.

Pulmonary disorders diagnosed following pulmonary function tests can be classified as:

• Obstructive conditions – a decreased flow of air due to increased airway resistance;
• Restrictive conditions – when lung tissue or chest muscles don’t expand sufficiently, thus leading to low lung volumes.

Conditions diagnosed following PFTs include:

• Allergies;
• Respiratory infections;
• Chronic lung conditions (asthma, bronchiectasis, emphysema, or chronic bronchitis);
• Sarcoidosis;
• Scleroderma;
• Restrictive airway problems from malignancy or inflammation or scarring of the lungs.

Some surgery procedures may require a set of PFTs to be performed before. PFT results may be less accurate if the patient doesn’t fully cooperate, if bronchodilators are used, if pain medicines are used, during pregnancy, if patient suffers from stomach bloating during tests or other conditions that may affect patient’s ability to follow the instructions.

Tidal Volume (TV)

Tidal volume is the measure of the amount of air inhaled during a normal breath. Safe tidal volumes can be determined based on patient’s height and gender and the rule of thumb of 6 to 8mL per kg of ideal body weight (IBW) where:

• `IBW male = 50kg + 2.3 x (Height in inches – 60)`
• `IBW female = 45.5kg + 2.3 x (Height in inches – 60)`

Normal range for measured tidal volume is 500 – 780 mL.

Minute Volume (VE)

Minute ventilation or minute volume, is defined as the total volume of gas entering (or leaving) the lung per minute and is calculated as product of tidal volume and respiratory rate.

• `VE in mL/min = Tidal volume (Vt) in mL x Respiratory rate (RR) in resp/min`

Normal range for minute volume is 70 – 110 mL/kg/min or in average adults (4.0 – 8.0 L/min).

Peak Expiratory Flow Rate (PEFR)

The peak expiratory flow rate predicts the maximum speed of expiration and offers information about the airflow through the bronchi, thus can quantify how severe the degree of airway obstruction is.

Peak expiratory flow is estimated via one of the three formulas, depending on the patient characteristics:

• `Children PEFR = ((Height in cm - 100) x 5) + 100`
• `Adult Men = (((Height in m x 5.48) + 1.58) - (Age x 0.041)) x 60`
• `Adult Women = (((Height in m x 3.72) + 2.24) - (Age x 0.03)) x 60`

Normal range in adults is between 390 and 740 L/min.

Forced Vital Capacity (FVC)

Forced vital capacity (FVC) is the total amount of air exhaled during the FEV test.

• `FVC = Race x 1.15 x [(0.0443 x Height) - (0.026 x Age) - 2.89]`

Where Race variables are: 0.93 for Asian, 0.87 for Black or African American and 1 for White Caucasian.

Normal range FEV1 is between 3.0 and 5.0 L

Forced Expiratory Volume (FEV1)

Forced expiratory volume (FEV1) measures how much air a person can exhale during the first second of a forced breath.

• `FEV1 = Race x 1.08 x [(0.0395 x Height) - (0.025 x Age) - 2.6]`

Where Race variables are: 0.93 for Asian, 0.87 for Black or African American and 1 for White Caucasian.

Normal range FEV1 is between 2.4 and 4.0 L. Lower FEV1 values are indicative of obstructive lung disease, such as asthma or COPD.

Estimated Vital Capacity

Vital capacity can be indirectly estimated based on gender, age and height in centimetres.

• `VC for men = [(27.63 – 0.112 x Age in years) x Height in cm] / 1000`
• `VC for women = [(21.78 – 0.101 x Age in years) x Height in cm] / 1000`

Subject age is taken into account as a factor because vital capacity increases during the 20s and 30s and then follows a steady decrease towards the 50s. The VC estimation is gender specific (men tend to have a higher volume than women) but the general normal range is between 3.0 and 5.0 L.

Pulmonary Capacities

During spirometry, the four respiratory volumes are measured: inspiratory reserve volume (IRV), tidal volume (TV), expiratory reserve volume (ERV) and residual volume (RV). These are then used to determine the lung capacities, defined as:

 Lung Capacity Formula Normal Range Vital Capacity (VC) IRV + TV + ERV 3.0 – 5.0 L Functional Residual Capacity (FRC) ERV + RV 2.0 – 4.0 L Total Lung Capacity (TLC) IRV + TV + ERV + RV 4.0 – 6.0 L

References

Blackie SP, Fairbarn MS, McElvaney NG, Wilcox PG, Morrison NJ, Pardy RL. Normal values and ranges for ventilation and breathing pattern at maximal exercise. Chest. 1991; 100(1):136-42.

Radeos MS, Camargo CA Jr. Predicted peak expiratory flow: differences across formulae in the literature. Am J Emerg Med. 2004; 22(7):516-21.

Godfrey MS, Jankowich MD. The Vital Capacity Is Vital: Epidemiology and Clinical Significance of the Restrictive Spirometry Pattern. Chest. 2016; 149(1):238-51.

Quanjer PhH, Tammeling GJ, Cotes JE, et al. Lung volume and forced ventilatory flows. Report Working Party Standardization of lung function tests. Official Statement European Respiratory Society. Eur Respir J. 1993; 6 Suppl 16: 5-40.

Falaschetti E, Laiho J, Primatesta P, Purdon S. Prediction equations for normal and low lung function from the Health Survey for England. Eur Respir J. 2004; 23(3):456-63.

Gommers D. Functional residual capacity and absolute lung volume. Curr Opin Crit Care. 2014; 20(3):347-51.

Flesch JD, Dine CJ. Lung volumes: measurement, clinical use, and coding. Chest. 2012; 142(2):506-10.

Ruppel GL. What is the clinical value of lung volumes? Respir Care. 2012; 57(1):26-35.

Techanivate A, Kumwilaisak K, Samranrean S. Estimation of the proper length of orotracheal intubation by Chula formula. J Med Assoc Thai. 2005; 88(12):1838-46.

Specialty: Pulmonology

System: Respiratory

No. Of Variables: 9

Abbreviation: PFT

Article By: Denise Nedea

Published On: June 12, 2020 · 12:00 AM

Last Checked: June 12, 2020

Next Review: June 12, 2025