Pediatric Blood Transfusion Volume Calculator

Determines blood transfusion volume (BTV) based on infant or child’s weight, hemoglobin increment and hematocrit.

Refer to the text below the tool for more information about the formula used.


Blood transfusion volume is usually estimated in adult patients by the rule of thumb that one unit of packed red blood cells (RBCs) raises the hemoglobin (Hb) concentration by 1 g/dL or the hematocrit by 3%.

However, because the blood volume of infants and children varies considerably, the pediatric BTV required to raise the Hb by 1 g/dL is lower than that needed for an adult.


A correlation gradient of 5.02 was found by Davies et al. between mL per kg blood transfused and increase in Hb.

In neonates and children less than 20kg, transfusion volumes are based on weight and prescribed in mLs. The equation is:

Transfusion Blood Volume = Weight (kg) x Hemoglobin increment x 3 / Hematocrit


Weight
Hemoglobin increment
Hematocrit
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Steps on how to print your input & results:

1. Fill in the calculator/tool with your values and/or your answer choices and press Calculate.

2. Then you can click on the Print button to open a PDF in a separate window with the inputs and results. You can further save the PDF or print it.

Please note that once you have closed the PDF you need to click on the Calculate button before you try opening it again, otherwise the input and/or results may not appear in the pdf.


 

Pediatric BTV Explained

Blood transfusion volume is usually estimated in adult patients by the rule of thumb that one unit of packed red blood cells (RBCs) raises the hemoglobin (Hb) concentration by 1 g/dL or the hematocrit by 3%.

However, because the blood volume of infants and children varies considerably, the pediatric BTV required to raise the Hb by 1 g/dL is lower than that needed for an adult.

Davies et al. devised an equation that allows accurate blood volume calculation by accounting for the increase in serum hemoglobin. Data from a cohort of 7,679 patients were examined, with a total of 564 transfusions.

A correlation gradient of 5.02 was found between mL per kg blood transfused and increase in Hb.

In neonates and children less than 20kg, transfusion volumes are based on weight and prescribed in mLs. The equation is:

Transfusion Blood Volume = Weight (kg) x Hemoglobin increment x 3 / Hematocrit

The table below summarizes normal pediatric hematocrit ranges:

Infant / Child’s age Hematocrit
One month 42 - 65%
Two months 33 - 55%
Three to six months 28 - 41%
Six to twelve months 31 - 41%
One to five years 31 - 44%
After five years 34 - 48%
 

References

Original reference

Davies P, Robertson S, Hegde S, Greenwood R, Massey E, Davis P. Calculating the required transfusion volume in children. Transfusion. 2007; 47(2):212-216.

Other references

Arslan O, Toprak S, Arat M, Kayalak Y. Hb content-based transfusion policy successfully reduces the number of RBC units transfused. Transfusion. 2004; 44(4):485-488.

Grant MJ, Huether SE, Witte MK. Effect of red blood cell transfusion on oxygen consumption in the anemic pediatric patient. Pediatr Crit Care Med. 2003; 4(4):459-464.


Specialty: Pediatrics

System: Circulatory

Year Of Study: 2007

Article By: Denise Nedea

Published On: August 13, 2020

Last Checked: August 13, 2020

Next Review: August 13, 2025