Oxygen Delivery Equation Calculator

Determines the amount of oxygen delivered to the capillaries per minute based on arterial oxygen content and cardiac output.


This oxygen delivery calculator computes the product between the arterial oxygen content (CaO2) and cardiac output (CO), which is the amount of oxygen delivered to the capillaries per minute, also known as oxygen delivery (DO2).


Oxygen Delivery (mL O2/min) = CaO2 x CO x 10

Normal Range Values

Variable Lower limit Higher limit
Arterial oxygen content (CaO2) 16 mL O2/100 mL 22 mL O2/100 mL
Cardiac output (CO) 4250 mL/min 6120 mL/min
Oxygen delivery (DO2) 750 mL O2/min 1200 mL O2/min

Arterial oxygen content (CaO2)
Cardiac output (CO)
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Steps on how to print your input & results:

1. Fill in the calculator/tool with your values and/or your answer choices and press Calculate.

2. Then you can click on the Print button to open a PDF in a separate window with the inputs and results. You can further save the PDF or print it.

Please note that once you have closed the PDF you need to click on the Calculate button before you try opening it again, otherwise the input and/or results may not appear in the pdf.


 

Oxygen delivery explained

Global oxygen delivery (DO2) is the total amount of oxygen delivered to the tissues in the entire body per minute, regardless of the distribution of blood flow. It is the product of total blood flow or cardiac output (CO) and the oxygen content of arterial blood and is usually expressed in ml O2/min.

Oxygen Delivery (mL O2/min) = CaO2 x CO x 10

From oxygen in the environment to feeding the tissues, the process has three steps: oxygenation, oxygen delivery and oxygen consumption.

Under normal resting conditions with normal cardiac output, the oxygen delivery is adequate as to meet oxygen consumption needs and ensure normal functioning of aerobic cellular metabolism. If there is a deficiency of oxygen at tissue level, it leads to tissue hypoxia.

Normal Range Values

Variable Lower limit Higher limit
Arterial oxygen content (CaO2) 16 mL O2/100 mL 22 mL O2/100 mL
Cardiac output (CO) 4250 mL/min 6120 mL/min
Oxygen delivery (DO2) 750 mL O2/min 1200 mL O2/min
 

References

Dantzker DR, Foresman B, Gutierrez G. Oxygen supply and utilization relationships. A reevaluation. Am Rev Respir Dis 1991; 143:675.

Shepherd AP, Granger HJ, Smith EE, Guyton AC. Local control of tissue oxygen delivery and its contribution to the regulation of cardiac output. Am J Physiol 1973; 225:747.

Kruse JA, Haupt MT, Puri VK, Carlson RW. Lactate levels as predictors of the relationship between oxygen delivery and consumption in ARDS. Chest 1990; 98:959.


Specialty: Pulmonology

System: Respiratory

Abbreviation: DO2

Article By: Denise Nedea

Published On: May 18, 2020

Last Checked: May 18, 2020

Next Review: May 18, 2025