Naproxen Dosage (Aleve Dose) Calculator

Helps with dosing this NSAID for pain and inflammation relief in a variety of conditions from migraine to bursitis or rheumatoid arthritis.

Refer to the text below the tool for more information about Naproxen properties, side effects and interactions.


Naproxen (commonly known under the commercial name Aleve) belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs) and is usually prescribed to relieve pain in several conditions, as well as reduce swelling and joint stiffness:

  • Pain (adults and children over 12);
  • Fever (adults and children over 12);
  • Rheumatoid arthritis;
  • Osteoarthritis;
  • Ankylosing spondylitis;
  • Migraine;
  • Dysmenorrhea;
  • Acute gout;
  • Bursitis;
  • Tendonitis;
  • Juvenile idiopathic arthritis.

Naproxen side effects

Abdominal pain Dizziness
Constipation Drowsiness
Swelling Headache
Abdominal bleeding Nausea
Abdominal perforation Light-headedness
Abdominal ulcers Difficulty breathing
Diarrhea Fluid retention

Indication
Formulation
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1. Fill in the calculator/tool with your values and/or your answer choices and press Calculate.

2. Then you can click on the Print button to open a PDF in a separate window with the inputs and results. You can further save the PDF or print it.

Please note that once you have closed the PDF you need to click on the Calculate button before you try opening it again, otherwise the input and/or results may not appear in the pdf.


 

Dosing Naproxen (Aleve)

Naproxen (commonly known under the commercial name Aleve) belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs) and is usually prescribed to relieve pain in several conditions, as well as reduce swelling and joint stiffness.

Naproxen may be used in alleviating symptoms of:

  • Pain (adults and children over 12);
  • Fever (adults and children over 12);
  • Rheumatoid arthritis;
  • Osteoarthritis;
  • Ankylosing spondylitis;
  • Migraine;
  • Dysmenorrhea;
  • Acute gout;
  • Bursitis;
  • Tendonitis;
  • Juvenile idiopathic arthritis.

It is important to note that NSAIDs may increase risk of serious cardiovascular thrombotic events, myocardial infarction and stroke, especially in patients with existing cardiovascular disease.

Naproxen possible formulations are summarized below:

  • OTC Regular Tablet 220 mg;
  • Regular Tablet 250 mg, 275 mg, 375 mg, 500 mg, 550 mg;
  • Oral Suspension 25 mg/mL;
  • Delayed Release Tablet 375 mg, 500 mg;
  • Controlled Release Tablet 375 mg, 500 mg, 750 mg.

Other brand names you may find Naproxen under, aside from Aleve, include:

  • Anaprox
  • E C Naprosyn
  • Equiproxen 10% Solution
  • Equiproxen Granules
  • Naproxen SR
  • Naprox Sodium
  • Menstridol

Common side effects of Naproxen therapy

Abdominal pain Dizziness
Constipation Drowsiness
Swelling Headache
Abdominal bleeding Nausea
Abdominal perforation Light-headedness
Abdominal ulcers Difficulty breathing
Diarrhea Fluid retention

As observed from the table of side effects, as a NSAID, Naproxen may increase risk of serious gastrointestinal adverse events (especially in elderly patients), which left untreated may lead to significant morbidity and mortality risk.

Naproxen has serious interactions with 15 other active substances: benazepril, captopril, enalapril, fosinopril, ketorolac, ketorolac intranasal, lisinopril, methotrexate, moexipril, pemetrexed, perindopril, quinapril, ramipril, tacrolimus and trandolapril. Moderate, respectively mild interactions have been observed with at least 229, respectively 80 other different drugs.

 

References

Brutzkus JC, Shahrokhi M, Varacallo M. Naproxen. [Updated 2020 May 24]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls.

Derry C, Derry S, Moore RA, McQuay HJ. Single dose oral naproxen and naproxen sodium for acute postoperative pain in adults. Cochrane Database Syst Rev. 2009; 2009(1):CD004234.


Specialty: Pharmacology

Article By: Denise Nedea

Published On: November 4, 2020

Last Checked: November 4, 2020

Next Review: November 4, 2025