Jelliffe Equation Calculator for Renal Function

Estimates creatinine clearance rate to assess renal function based on serum creatinine, patient age, gender and body surface area.

Refer to the text below the tool for more information about the formula and its usage.

The estimated creatinine clearance rate (eCCr) based on the 1973 equation by Jelliffe may be used to assess unstable renal function in patients of 20 to 80 years old.

However, the formula has nowadays become deprecated in favor of newer equations, examples of which can be found at the end of text below the calculator.

The estimated creatinine clearance rate (eCCr) based on the 1973 equation by Jelliffe is:

eCCr = ((98 – 0.8 x (Age – 20)) x (1 – (0.1 x Gender)) x (BSA/1.73)) / (Serum creatinine in µmol/L x 0.0113)

CrCl normal values are around 97-137 ml/min in men and 88-128 mL/min in women. Abnormal increases in CrCl may be indicative of some kind of renal dysfunction, either of filtration, existence of infection, reduced blood flow, dehydration or muscular problems.

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Steps on how to print your input & results:

1. Fill in the calculator/tool with your values and/or your answer choices and press Calculate.

2. Then you can click on the Print button to open a PDF in a separate window with the inputs and results. You can further save the PDF or print it.

Please note that once you have closed the PDF you need to click on the Calculate button before you try opening it again, otherwise the input and/or results may not appear in the pdf.

Jelliffe GFR Equation Explained

When the serum creatinine level is stable, in adult patients from 20 to 80 years old, it may be used to assess renal function by estimating the creatinine clearance rate. The estimated creatinine clearance rate (eCCr) based on the 1973 equation by Jelliffe is:

eCCr in ml/min = ((98 – 0.8 x (Age – 20)) x (1 – (0.1 x Gender)) x (BSA/1.73)) / (Serum creatinine in µmol/L x 0.0113)

Where:

Gender value is 0 for men and 1 for women;
BSA (DuBois’s formula) = (0.007184 x (Height in cm)⁷²⁵ x (Weight in kg)^0.425);
Serum creatinine is expressed in µmol/L. In case the serum creatinine is given in mg/dL, the conversion from mg/dL to µmol/L is: 1 mg/dL = 88.4 µmol/L.

The Jelliffe equation does not require a patient's height or weight because it describes unstable renal function normalized to a body surface area of 1.73 m². It is now considered deprecated in favor of newer equations.

Other ways of estimating creatinine clearance or glomerular filtration rate include:

The Cockcroft-Gault formula (gold standard);
The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI);
The MDRD equation (studied in patients with renal dysfunction (GFR < 60 mL/min/1.73 m²);
The Wright formula.

References

Original reference

Jelliffe R. Letter: Creatinine clearance: bedside estimate. Ann Intern Med. 1973; 79(4):604-5.

Other references

Jelliffe R. Estimation of creatinine clearance in patients with unstable renal function, without a urine specimen. Am J Nephrol. 2002; 22(4):320-4.

Bouchard J, Macedo E, Soroko S, Chertow GM, Himmelfarb J, Ikizler TA, Paganini EP, Mehta RL; Program to Improve Care in Acute Renal Disease. Comparison of methods for estimating glomerular filtration rate in critically ill patients with acute kidney injury. Nephrol Dial Transplant. 2010; 25(1):102-7.

Marx GM, Blake GM, Galani E, Steer CB, Harper SE, Adamson KL, Bailey DL, Harper PG. Evaluation of the Cockroft-Gault, Jelliffe and Wright formulae in estimating renal function in elderly cancer patients. Ann Oncol. 2004; 15(2):291-5.

DuBois D, DuBois DF. A formula to estimate the approximate surface area if height and weight be known. Arch Int Med 1916; 17:863-71.

Specialty: Nephrology

System: Renal

Year Of Study: 1973

Article By: Denise Nedea

Published On: October 25, 2020 · 12:00 AM

Last Checked: October 25, 2020