Clomid Ovulation Calculator

Clomid administration and ovulation

As most recommendations suggest that the fertility treatment with Clomiphene citrate to begin during the 3^rd to 5^th of a new menstrual cycle and last for a period of 5 days, the date for induced ovulation is set to be approximately 7 days after the last dose of Clomid.

Clomiphene citrate action on triggering ovulation is based on changing the biochemical balance in the body and limiting availability of estrogen. This tricks the body into releasing GnRH, the hormone responsible with regulating FSH and LH, the hormones that induce ovulation (in 80% of cases).

Clomid is usually prescribed for ovulatory dysfunctions, such as those occurring in the case of PCOS (Polycystic Ovarian Syndrome).

Planning a pregnancy when on therapy with Clomiphene citrate means that couple should start having intercourse every other day (after the fifth day of treatment) and continue the pattern for another 10 days, to increase the chances of conception during that menstrual cycle. The rate of pregnancies occurring during the first six cycles with Clomid is between 40 and 50%.

Therapy with ovulation stimulants can have different side effects, one of the most common being that it leads to an increased likelihood of multiple pregnancy, an increase in risk of ectopic pregnancy or birth defects.

There are other effects of concern, however, usually of mild severity, that include stomach pain with or without bloating and abdominal discomfort, fatigue, hot flashes, breast tenderness, nausea and vomiting, weight gain (in less than 1%) or mood swings.

Clomid therapy should not continue past 6 cycles or if any of the side effects occur and alternative reproductive solutions should be sought.

References

Kerin JF, Warnes GM, Quinn P, Jeffrey R, Godfrey B, Broom TJ, McEvoy M, Kirby C, Johnson M, Cox LW. (1983) The effect of clomid induced superovulation on human follicular and luteal function for extracorporeal fertilization and embryo transfer. Clin Reprod Fertil; 2(2):129-42.

Feichtinger W, Kemeter P, Hochfellner C, Benkö I. (1983) Monitoring of Clomid-hMG-hCG controlled ovulation by ultrasound and a rapid (15 minutes) total urinary estrogen assay. Acta Eur Fertil; 14(2):107-11.

Seyedoshohadaei F, Zandvakily F, Shahgeibi S. (2012) Comparison of the effectiveness of clomiphene citrate, tamoxifen and letrozole in ovulation induction in infertility due to isolated unovulation. Iran J Reprod Med; 10(6): 531–536.