Absolute Eosinophil Count Calculator

Determines the total number of acidophilic cells from white blood cell count and eosinophil percentage.

Refer to the text below the tool for more information about the eosinophil count.


The white blood cell (WBC) count and the eosinophil percentage can be used to estimate the total number of the acidophilic cells in a blood sample.

Eosinophils are involved in immunity response to parasites and are mediators of allergic responses, are used as markers of disease severity, as well as associated with bronchial asthma development.


Absolute Eosinophil Count = WBC x Eosinophils / 100

Parameter Normal Low Normal High
White Blood Cells (WBC) 4.1  x103/μL 10.9  x103/μL
Eosinophils % 0.1% 6.0%
Absolute Eosinophil Count 0.041 x103/μL 0.654 x10³/μL

White Blood Cells (WBC)
Eosinophils
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About Absolute Eosinophil Count

The white blood cell (WBC) count and the eosinophil percentage can be used to estimate the total number of the acidophilic cells in a blood sample.

Eosinophils are granulocytes and generally make up about 1-5 % of the circulating leukocytes. This type of cells is also known as acidophilic because it shows affinity for acids and is full of spherical acidophilic granules. The normal range is between 0.04 and 0.65 x10³/μL.

The function of eosinophils is phagocytosis of antigen-antibody complexes, as well as multiple roles, such as:

  • Markers of disease severity;
  • Immunity response to parasites;
  • Mediators of allergic responses;
  • Involvement in bronchial asthma development.

To compute the AEC, a complete blood count test is required, which will reveal the WBC and eosinophil percentage, further used in:

Absolute Eosinophil Count = WBC x Eosinophils / 100

Reference Ranges

Parameter Normal Low Normal High
White Blood Cells (WBC) 4.1 x103/μL 10.9 x103/μL
Eosinophils % 0.1% 6.0%
Absolute Eosinophil Count 0.041 x103/μL 0.654 x10³/μL

Eosinophil Count by Age

Age AEC
Neonates 0 - 0.9 x103/μL
Infants 1 week to 6 months 0.2 - 0.3 x103/μL
Infants, 12 months 0.3 x103/μL
Infants, 24 months 0 - 0.7 x103/μL
Children 0 - 0.6 x103/μL

An abnormal increase in the number of eosinophils is called eosinophilia and may be associated with:

  • Allergic and drug reactions;
  • Parasitic infestations;
  • Some skin disorders;
  • Collagen vascular diseases;
  • Myeloproliferative diseases;
  • Hodgkin’s disease.

An abnormal decrease in the number of eosinophils is called eosinopenia and may be observed in:

  • Hyperadrenalism;
  • Glucocorticoid administration;
  • Acute bacterial infection;
  • Physical stress.

Absolute cell counts can be estimated for Neutrophils as well as for Lymphocytes.

 

References

LaGow B et al., eds. PDR Lab Advisor. A Comprehensive Point-of-Care Guide for Over 600 Lab Tests. First ed. Montvale, NJ: Thomson PDR; 2007.

Pagana K, Pagana TJ eds. Mosby's Manual of Diagnostic and Laboratory Tests. 5th Ed. St. Louis, Missouri. 2014.

Brigden M, Graydon C. Eosinophilia detected by automated blood cell counting in ambulatory North American outpatients. Incidence and clinical significance. Arch Pathol Lab Med. 1997; 121(9):963-967.

Kovalszki A, Weller PF. Eosinophilia. Prim Care. 2016; 43(4):607-617.

Ramirez GA, Yacoub MR, Ripa M, Mannina D, Cariddi A, Saporiti N, Ciceri F, Castagna A, Colombo G, Dagna L. Eosinophils from Physiology to Disease: A Comprehensive Review. Biomed Res Int. 2018; 2018:9095275.


Specialty: Hematology

System: Circulatory

Article By: Denise Nedea

Published On: June 26, 2020

Last Checked: June 26, 2020

Next Review: June 26, 2025